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MicroRNA-16 feedback loop with p53 and Wip1 can regulate cell fate determination between apoptosis and senescence in DNA damage response.

机译：具有p53和Wip1的microRNa-16反馈环可以调节DNa损伤反应中细胞凋亡和衰老之间的细胞命运决定。

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Maria Vitória C Issler; José Carlos M Mombach;
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年度 2017
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1. Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication [J] . SakaiH., FujigakiH., MazurS.J., Cell cycle . 2014,第6期

机译：野生型p53诱导的磷酸酶1（Wip1）通过调节DNA复制过程中的DNA损伤反应信号传导，在生理氧水平上阻止细胞过早衰老。
2. Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response. [J] . Gatti L, Supino R, Perego P, Cell death and differentiation . 2002,第12期

机译：U2-OS细胞中铂化合物诱导的细胞凋亡和生长停滞反映了与不同p53介导的反应相关的特定DNA损伤识别。
3. p53 directly transactivates Delta133p53alpha, regulating cell fate outcome in response to DNA damage. [J] . Aoubala M, Murray Zmijewski F, Khoury MP, Cell death and differentiation . 2011,第2期

机译：p53直接激活Delta133p53alpha，调节细胞命运以响应DNA损伤。
4. The Study on Targeted Drug Regulation on DNA Methylation of p53-Bax Mitochondrial Apoptosis Pathway Enhances Chemo- Sensitivity of Cholangiocarcinoma Cells [C] . Xiao-fang Liu, Shao-ping Yu, Xian-chun Sun, Proceedings of the world medical conference . 2010

机译：p53-Bax线粒体细胞凋亡途径DNA甲基化的靶向药物调控增强胆管癌细胞化学敏感性的研究
5. The Cell's Fate, Apoptosis or Senescence, Depends on Dose and Duration of Exposure to DNA Damaging Agents such as Mitomycin C. [D] . McKenna, Elise. 2012

机译：细胞的命运，凋亡或衰老取决于剂量和暴露于DNA破坏剂（如丝裂霉素C）的持续时间。
6. MicroRNA-16 feedback loop with p53 and Wip1 can regulate cell fate determination between apoptosis and senescence in DNA damage response [O] . Maria Vitória C. Issler, José Carlos M. Mombach -1

机译：具有p53和Wip1的MicroRNA-16反馈环可以调节细胞命运在DNA损伤反应中凋亡和衰老之间的确定
7. Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication [O] . Hiroyasu Sakai, Hidetsugu Fujigaki, Sharlyn Mazur, 2014

机译：野生型P53诱导的磷酸酶1（WIP1）通过调节DNA复制期间通过调节DNA损伤响应信号来调节生理氧水平的细胞过早衰老
8. Susceptibility to Radiation Induced Apoptosis and Senescence in p53 Wild Type and p53 Mutant Breast Tumor Cells [R] . DeMasters, G. 2006

机译：p53野生型和p53突变乳腺癌细胞辐射诱导细胞凋亡和衰老的易感性

MicroRNA-16 feedback loop with p53 and Wip1 can regulate cell fate determination between apoptosis and senescence in DNA damage response.

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